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Bauhinia candicans stimulation of glucose uptake in isolated gastric glands of normal and diabetic rabbits.

Fuentes O, Alarcón J

Laboratorio de Fisiología, Facultad de Ciencias, Universidad del Bío-Bío, Campus Chillán, Avenida Andrés Bello s/n, P.O. Box 447, Chillán, Chile. ofuentes@ubiobio.cl

A butanol extract of dried leaves of Bahuinia candicans showed, in vitro, a stimulatory effect of glucose uptake in isolated gastric glands of normal and alloxan-diabetic rabbits. The extract (0.001-0.07 mg/mg protein) produced a dose-dependent effect and was similar to the effect of insulin (1-100 nM). These findings suggest that the extract contains compound(s) that efficiently increase glucose transport at the basolateral side of isolated gastric glands.

Published 5 June 2006 in Fitoterapia, 77(4): 271-5.
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